Mammalian skin often contains hairs, which in sufficient density is called fur. The hair mainly serves to augment the insulation the skin provides, but can also serve as a secondary sexual characteristic or as camouflage. On some animals the skin is very hard and thick, and can be processed to create leather. Reptiles and fish have hard protective scales on their skin for protection, and birds have hard feathers, all made of tough β-keratins. Amphibian skin is not a strong barrier to passage of chemicals. A frog sitting in an anesthetic solution will quickly go to sleep. The outermost epidermis is consists of stratified squamous epithelium with an underlying basement membrane. It contains no blood vessels, and is nourished by diffusion from the dermis. The main type of cells which make up the epidermis are keratinocytes, with melanocytes and Langerhans cells also present. The epidermis can be further subdivided into the following strata (beginning with the outermost layer): corneum, lucidum, granulosum, spinosum, basale. Cells are formed through mitosis at the innermost layers. They move up the strata changing shape and composition as they differentiate, inducing expression of new types of keratin genes. They eventually reach the corneum and become sloughed off (desquamation). This process is called keratinization and takes place within about 30 days. This layer of skin is responsible for keeping water in the body and keeping other harmful chemicals and pathogens out. Skin can be dividided into thick and thin types. Thick skin is present on the soles of the feet and the palms of the hands. It has a larger stratum corneum with a higher keratin content. Thick skin does not grow hair; its purpose is to help grip. Thin skin is present on the bulk of the body and has a smaller stratum corneum and fewer papillae ridges. It has hair and is softer and more elastic. The characteristics of the skin, including sensory nerve density and the type of hair, vary with location on the body. If you take care of your skin, your skin will take care of you! But with all of the lotions, creams, and potions on the market, it can be difficult to know which product will work for you. Many products claim to remove wrinkles or heal dry skin. Others claim to contain expensive ingredients that they say will improve the effects of the product. As we age, our body undergoes various changes, and so does our skin. In our skin, we have tissues known as collagen and elastin. These tissues are mainly responsible for making our skin firm and stretchable. As we grow older, the amount of collagen and elastin in our skin naturally diminishes. As a result, our skin becomes less elastic and weaker, thus creating "wrinkles". There are a lot of skin care products in the market today. Unlike before when a normal bar of soap was used for skin cleansing, cosmetic companies are now producing a wide variety of skin care treatments that can address various skin concerns. However, there are cases when treatments need to be more aggressive, especially for those who have aging or blemished skin. Most, if not all, of the over-the-counter products are topical in nature, meaning it only affects the epidermis or the outer layer of the skin. Aging or blemished skin needs to be treated down to the root of the problem to see definite changes.
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